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Hereditary spastic paraplegia

genetically and clinically heterogeneous group of neurodegenerative disorders characterized by progressive spasticity and hyperreflexia of the lower limbs

Pronunciation
/hɪˈrɛdɪtəri ˈspastɪk ˌparəˈpliːʤə/
/həˈrɛdəˌtɛri ˈspæstɪk ˌpɛrəˈpliʤiə/