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Systemic scleroderma

scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies

Pronunciation
/sɪˈstiːmɪk ˌsklɪərəˈdəːmə/
/səˈstɛmɪk ˌsklɛrəˈdərmə/